Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016918 | 0.78 | HPGD (0.38) | CHEK1SQORBRD4NPC1RAB9A | |
| SCHEMBL11026081 | 0.78 | PARP1 (0.50) | PDE9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29827689 | 0.77 | KDM4E (0.50) | CHEK1SQORNPC1RAB9APDE9A | |
| SCHEMBL11020788 | 0.77 | LRRK2 (0.42) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL11023115 | 0.75 | PDE3B (0.50) | SQORMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL11020771 | 0.74 | KDM4E (0.46) | SQORMETKDM4EALDH1A1HPGD | |
| SCHEMBL11019014 | 0.72 | HTT (0.49) | SQORMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6535826 | 0.72 | CHEK1 (0.46) | CHEK1BRD4NPC1RAB9AMAPT | |
| SCHEMBL22316413 | 0.70 | SQOR (0.38) | SQORNPC1RAB9AMAPTMITF | |
| SCHEMBL11023464 | 0.70 | KDM4E (0.46) | MAPTKDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |