Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | HPGD | P15428 | 4/20 | 0.75 |
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | MTOR | P42345 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.75 |
| ▸ | GMNN | O75496 | 1/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | IDE | P14735 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019366 | 1.00 | TRPV1 (0.81) | TRPV1ALOX12MAPTHPGDTP53 | |
| SCHEMBL10713028 | 0.98 | TRPV1 (0.85) | TRPV1ALOX12MAPTHPGDTP53 | |
| SCHEMBL10068244 | 0.90 | TRPV1 (1.00) | TRPV1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL10068349 | 0.90 | TRPV1 (1.00) | TRPV1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL10068102 | 0.90 | TRPV1 (1.00) | TRPV1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL28719248 | 0.90 | TRPV1 (1.00) | TRPV1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL29550109 | 0.90 | TRPV1 (1.00) | TRPV1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL10068245 | 0.90 | TRPV1 (1.00) | TRPV1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL10038328 | 0.90 | TRPV1 (1.00) | TRPV1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL3693269 | 0.88 | ALOX12 (1.00) | TRPV1ALOX12MAPTHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544669-A | ALKADIENAMIDES | THE PROCTER & GAMBLE COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0132346-A1 | Novel compounds and compositions useful for producing analgesia | THE PROCTER & GAMBLE COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |