Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MTOR | P42345 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | GMNN | O75496 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068102 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL28719248 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL29550109 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10068244 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10068245 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10068349 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10713028 | 0.92 | TRPV1 (0.85) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10886809 | 0.92 | TRPV1 (0.85) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL11019366 | 0.90 | TRPV1 (0.81) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL11019361 | 0.90 | TRPV1 (0.81) | TRPV1MAPTHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016116603-A1 | NOVEL PHENYLPHOSPHATES AND USE THEREOF AS MEDICAMENTS | UNIVERSITÄT LEIPZIG (DE) | 2016-07-28 | — | — | WO | disclosed |
| WO-2016116603-A1 | NOVEL PHENYLPHOSPHATES AND USE THEREOF AS MEDICAMENTS | UNIVERSITÄT LEIPZIG (DE) | 2016-07-28 | — | — | WO | disclosed |
| US-8703822-B2 | Method for removing undifferentiated and dedifferentiated stem cell | NANYANG POLYTECHNIC (SG) | 2014-04-22 | — | — | US | disclosed |
| US-8703822-B2 | Method for removing undifferentiated and dedifferentiated stem cell | NANYANG POLYTECHNIC (SG) | 2014-04-22 | — | — | US | disclosed |
| US-20120083532-A1 | NOVEL USES | NANYANG POLYTECHNIC (SG) | 2012-04-05 | — | — | US | disclosed |
| US-20120083532-A1 | NOVEL USES | NANYANG POLYTECHNIC (SG) | 2012-04-05 | — | — | US | disclosed |
| WO-2010144055-A1 | NOVEL COMPOUNDS AND USES THEREOF | NANYANG POLYTECHNIC (SG) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010144059-A2 | NOVEL USES | NANYANG POLYTECHNIC (SG) | 2010-12-16 | — | — | WO | disclosed |
| EP-0089710-B1 | NOVEL HYDROXYPHENYLACETAMIDES HAVING ANALGESIC AND ANTI-IRRITANT ACTIVITY | THE PROCTER & GAMBLE COMPANY (US) | 1985-07-31 | — | — | EP | disclosed |
| US-4424205-A | DEPILLATORIES | THE PROCTER & GAMBLE COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0089710-A1 | Novel hydroxyphenylacetamides having analgesic and anti-irritant activity | THE PROCTER & GAMBLE COMPANY (US) | 1983-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083532-A1 | NOVEL USES | PYCR1, CYP11B2, IL4I1 | TRPV1 1965/4885MAPT 4441/4885HSD17B10 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.