SCHEMBL11019488

SCHEMBL11019488

Cc1ccc(Oc2ccc(C(=O)C=CC(=O)O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.79
MAPT P10636 7/20 0.79
HTT P42858 4/20 0.79
NPSR1 Q6W5P4 3/20 0.79
HPGD P15428 3/20 0.79
LMNA P02545 2/20 0.79
THRB P10828 1/20 0.79
SMN1; SMN2 Q16637 3/20 0.66
PKM P14618 2/20 0.66
ATM Q13315 2/20 0.66
KMT2A Q03164 2/20 0.66
NLRP1 Q9C000 1/20 0.66
MEN1 O00255 1/20 0.66
NTSR1 P30989 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
NPC1 O15118 3/20 0.54
POLB P06746 3/20 0.54
RAB9A P51151 3/20 0.54
MAOB P27338 2/20 0.54
MAOA P21397 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11019485 1.00 ALDH1A1 (0.79) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL711570 0.89 ALDH1A1 (1.00) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL711571 0.89 ALDH1A1 (1.00) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL16226344 0.89 ALDH1A1 (1.00) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL10938343 0.88 ALDH1A1 (0.77) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL10938338 0.88 ALDH1A1 (0.77) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL11020485 0.86 F3 (0.60) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL11020483 0.86 F3 (0.60) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL11018372 0.86 ALDH1A1 (0.66) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL11018369 0.86 ALDH1A1 (0.66) ALDH1A1MAPTHTTNPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0088585-B1 3-BENZOYL-2-MERCAPTOPROPIONIC ACID DERIVATIVES TAISHO PHARMACEUTICAL CO. LTD (JP) 1985-01-23 EP disclosed
US-4472316-A ANTILIPEMIC AGNETS TAISHO PHARMACEUTICAL CO., LTD. (JP) 1984-09-18 US disclosed
EP-0088585-A1 3-Benzoyl-2-mercaptopropionic acid derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1983-09-14 EP disclosed