SCHEMBL711571

SCHEMBL711571

Cc1ccc(C(=O)C=CC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
MAPT P10636 7/20 1.00
HTT P42858 4/20 1.00
NPSR1 Q6W5P4 3/20 1.00
HPGD P15428 3/20 1.00
LMNA P02545 2/20 1.00
THRB P10828 2/20 1.00
PKM P14618 2/20 0.83
ATM Q13315 2/20 0.83
KMT2A Q03164 2/20 0.83
SMN1; SMN2 Q16637 2/20 0.83
NLRP1 Q9C000 1/20 0.83
MEN1 O00255 1/20 0.83
NTSR1 P30989 1/20 0.83
TDP1 Q9NUW8 1/20 0.83
CYP1B1 Q16678 1/20 0.61
RAB9A P51151 3/20 0.61
NPC1 O15118 2/20 0.61
POLB P06746 2/20 0.61
ALOX12 P18054 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16226344 1.00 ALDH1A1 (1.00) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL711570 1.00 ALDH1A1 (1.00) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL28984937 0.91 ALDH1A1 (1.00) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL10934752 0.89 MAPT (0.79) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL11019485 0.89 ALDH1A1 (0.79) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL10934745 0.89 MAPT (0.79) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL11019488 0.89 ALDH1A1 (0.79) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL10938343 0.88 ALDH1A1 (0.77) ALDH1A1MAPTHTTNPSR1HPGD
SCHEMBL10938338 0.88 ALDH1A1 (0.77) ALDH1A1MAPTHTTNPSR1HPGD
P-Xylene SCHEMBL6232601 0.86 ALDH1A1 (0.74) ALDH1A1MAPTHTTNPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-109053726-A A kind of preparation method of zolpidem acid 烟台万润药业有限公司 2018-12-21 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-6916890-B1 Thermally reworkable epoxy resins and compositions based thereon HENKEL CORPORATION (US) 2005-07-12 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
WO-2003031492-A1 THERMALLY REWORKABLE EPOXY RESINS AND COMPOSITIONS BASED THEREO N HENKEL CORPORATION (US) 2003-04-17 WO claimed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 US disclosed
EP-0089650-A1 Process for producing antifungal pyridazinone derivatives and certain novel compounds produced by such a process SANKYO COMPANY LIMITED (JP) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885MAPT 2153/4885HTT 1387/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC ALDH1A1 4675/4885MAPT 2945/4885HTT 2995/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885MAPT 2153/4885HTT 1387/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 ALDH1A1 1569/4885MAPT 4074/4885HTT 4009/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 ALDH1A1 1723/4885MAPT 539/4885HTT 581/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885MAPT 2153/4885HTT 1387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.