Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 5/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999774 | 0.83 | SIGMAR1 (0.42) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL7649513 | 0.82 | PIM1 (0.42) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL7649510 | 0.82 | PIM1 (0.42) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL7649520 | 0.82 | PIM1 (0.42) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL5568863 | 0.82 | HDAC1 (0.47) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL3544732 | 0.78 | HTR2C (0.41) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL1738842 | 0.78 | HTR2C (0.41) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL6802931 | 0.77 | SIGMAR1 (0.49) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL3557231 | 0.77 | SIGMAR1 (0.49) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 | |
| SCHEMBL3434216 | 0.76 | MAPT (0.42) | SIGMAR1HTR2CHTR2BHTR2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134338-A1 | Process for preparing polyol-catalyst mixtures useful in the preparation of rigid polyurethane cellular products | TEXACO DEVELOPMENT CORPORATION (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4465791-A | REACTING WATER, A MANNICH BASE COMPOUND AND AN EPOXIDE | TEXACO INC. (PARENT) (US) | 1984-08-14 | — | — | US | disclosed |
| US-4404121-A | REACTING A MANNICH BASE WITH WATER AND AN EPOXIDE | TEXACO INC. (US) | 1983-09-13 | — | — | US | disclosed |