Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sodium Lauryl Sulfate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | CA1 | P00915 | 10/20 | 0.59 |
| ▸ | CA2 | P00918 | 10/20 | 0.59 |
| ▸ | CA9 | Q16790 | 8/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA7 | P43166 | 3/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | CA3 | P07451 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
| ▸ | FGF1 | P05230 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134676 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL11130202 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390764 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL11459438 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL25262176 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL27390 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL23387500 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390632 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390687 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390647 | 1.00 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 995422 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433006-B1 | — | — | None | — | — | US | claimed |
| US-6444628-B1 | — | — | None | — | — | US | claimed |
| US-6436383-B1 | — | — | None | — | — | US | claimed |
| US-9975808-B2 | Ultra-light cementitious compositions and related methods | UNITED STATES GYPSUM COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-9976170-B2 | Method for evaluating bacterial cell wall integrity | UNIVERSIDAD AUTONOMA DE MADRID (ES) | 2018-05-22 | — | — | US | claimed |
| US-9974748-B2 | Reduction of flake-like aggregation in nanoparticulate active agent compositions | ALKERMES PHARMA IRELAND LIMITED (IE) | 2018-05-22 | — | — | US | claimed |
| US-9974730-B2 | Oral care compositions and methods | COLGATE-PALMOLIVE COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-9974780-B2 | Solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and a coformer, compositions and methods of use thereof | CELGENE CORPORATION (US) | 2018-05-22 | — | — | US | claimed |
| US-20180133118-A1 | Oral Compositions Containing Gel Networks | PROCTER & GAMBLE (US) | 2018-05-17 | — | — | US | claimed |
| US-20180133166-A1 | MODIFIED-RELEASE THERAPEUTIC SYSTEMS FOR ORAL ADMINISTRATION OF MENTHOL IN THE TREATMENT OF INTESTINAL DISORDERS | MOGON PHARMACEUTICALS SAGL (CH) | 2018-05-17 | — | — | US | claimed |
| US-3957662-A | MAGNESIUM OR CALCIUM STEARATE | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | claimed |
| US-3956138-A | SURFACTANTS, LIPOPHILIC AGENT | CROCKETT FRED BENTON | 1976-05-11 | — | — | US | claimed |
| US-3954962-A | VISCOSITY ADJUSTERS, NON-AQUEOUS | Tripp, Alan R. (US) | 1976-05-04 | — | — | US | claimed |
| US-3950133-A | POLYOXYALKYLENE, CATALYST | MALLINCKRODT, INC. (US) | 1976-04-13 | — | — | US | claimed |
| US-3949560-A | BENTONITE; PHOSPHATE, SULFATE OR SALT OF LEONARDITE DISPERSANT; POLYMER | AMERICAN COLLOID COMPANY (US) | 1976-04-13 | — | — | US | claimed |
| US-3946108-A | CLARITY, DEGASSING, SUSPENDING AIR OR NITROGEN BUBBLES | COLGATE-PALMOLIVE COMPANY (US) | 1976-03-23 | — | — | US | claimed |
| US-3944511-A | Chemically modified polymers | OWENS-ILLINOIS, INC. (US) | 1976-03-16 | — | — | US | claimed |
| US-3943954-A | Pipeline transportation of viscous hydrocarbons | TEXACO INC. (US) | 1976-03-16 | — | — | US | claimed |
| US-3937321-A | Toothpaste | COLGATE-PALMOLIVE COMPANY (US) | 1976-02-10 | — | — | US | claimed |
| US-3935307-A | POLYSACCHARIDE | TEIJIN LIMITED (JA) | 1976-01-27 | — | — | US | claimed |