Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15923096 | 0.92 | HPGD (0.81) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL10676300 | 0.89 | HPGD (0.64) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL11021052 | 0.88 | HPGD (0.66) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL11018700 | 0.86 | RAB9A (0.64) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL11021740 | 0.86 | RAB9A (0.64) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL10678991 | 0.84 | RAB9A (0.61) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL11023229 | 0.84 | RAB9A (0.57) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL10679823 | 0.83 | HPGD (0.56) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL10527237 | 0.83 | RAB9A (0.59) | HPGDTSHRRAB9ANPC1L3MBTL1 | |
| SCHEMBL11021192 | 0.83 | RAB9A (0.59) | HPGDTSHRRAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |