Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018700 | 0.89 | RAB9A (0.64) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL11021740 | 0.87 | RAB9A (0.64) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL11020150 | 0.84 | HPGD (0.68) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL11024159 | 0.84 | MAOB (0.48) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL15923096 | 0.84 | HPGD (0.81) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL11021052 | 0.83 | HPGD (0.66) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL11021329 | 0.82 | L3MBTL1 (0.43) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL10678991 | 0.82 | RAB9A (0.61) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL10676300 | 0.82 | HPGD (0.64) | RAB9AHPGDTSHRNPC1L3MBTL1 | |
| SCHEMBL10679823 | 0.81 | HPGD (0.56) | RAB9AHPGDTSHRNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |