SCHEMBL11020159

SCHEMBL11020159

CCNC(=O)NCC#CC#CCNC(=O)NCC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.38
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
EPHX1 P07099 5/20 0.34
KMT2A Q03164 1/20 0.34
EPHX2 P34913 3/20 0.34
FAAH O00519 1/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28412690 0.81 EPHX1 (0.54) MCL1ALDH1A1SMN1; SMN2MMP1MMP2
SCHEMBL320068 0.81
SCHEMBL28293734 0.81 MMP1 (0.48) MCL1ALDH1A1SMN1; SMN2MMP1MMP2
SCHEMBL28407900 0.78 EPHX1 (0.63) MMP1MMP2EPHX1EPHX2
SCHEMBL7749581 0.77
SCHEMBL28417155 0.76 EPHX1 (0.69) SMN1; SMN2EPHX1EPHX2
SCHEMBL11573366 0.76 EPHX1 (0.39) MCL1ALDH1A1EPHX1KMT2AEPHX2
SCHEMBL2705473 0.75
SCHEMBL2699167 0.75
SCHEMBL28409771 0.75 EPHX1 (0.48) ALDH1A1MMP1MMP8EPHX1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269128-B Synthesis method of 1,1' - (hexa-2, 4-diyne-1, 6-diyl) bis (3-alkyl urea) compound 苏州爱玛特生物科技有限公司 2022-08-30 CN disclosed
CN-111269128-A Synthesis method of 1, 1' - (hexa-2, 4-diyne-1, 6-diyl) bis (3-alkyl urea) compound 苏州爱玛特生物科技有限公司 2020-06-12 CN disclosed
EP-0149784-A2 Process for transferring color-changing coating uniformly onto indicator and transfer ribbon therefore ALLIED CORPORATION (US) 1985-07-31 EP disclosed