SCHEMBL11020176

SCHEMBL11020176

CCC(C(O)=S)C(Cc1ccccc1)(C(O)=S)c1nc2ccccc2[nH]1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
GAA P10253 2/20 0.38
AR P10275 2/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
DDAH1 O94760 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
TXN P10599 1/20 0.36
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11020178 0.92 SMN1; SMN2 (0.43) NPSR1RAB9ANPC1GAAALDH1A1
SCHEMBL11017585 0.89 NPSR1 (0.40) NPSR1RAB9ANPC1GAAAR
SCHEMBL11023485 0.89 NPSR1 (0.42) NPSR1RAB9ANPC1KDM4EALDH1A1
SCHEMBL11017589 0.83 KMT2A (0.43) NPSR1RAB9ANPC1GAAAR
SCHEMBL11023488 0.81 SMN1; SMN2 (0.45) NPSR1RAB9ANPC1GAAKDM4E
SCHEMBL11019368 0.76 NPC1 (0.39) NPSR1RAB9ANPC1GAAKDM4E
SCHEMBL11018472 0.76 NPC1 (0.39) NPSR1RAB9ANPC1GAAKDM4E
SCHEMBL11017240 0.75 ALDH1A1 (0.38) NPSR1RAB9ANPC1KDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL11018208 0.74 NPSR1 (0.44) NPSR1RAB9ANPC1ALDH1A1POLB
SCHEMBL11018499 0.72 ALDH1A1 (0.43) NPSR1RAB9ANPC1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed