SCHEMBL11019368

SCHEMBL11019368

CCCCCCCCCCCCCCCCCCC(C(O)=S)C(CCCCCCCCCCCCCCCCCC)(C(O)=S)c1nc2ccccc2[nH]1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SPHK2 Q9NRA0 1/20 0.39
SPHK1 Q9NYA1 1/20 0.39
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
DAGLA Q9Y4D2 1/20 0.38
BCHE P06276 1/20 0.37
TRPC3 Q13507 1/20 0.37
TRPC4 Q9UBN4 1/20 0.37
TRPC5 Q9UL62 1/20 0.37
KDM4E B2RXH2 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.35
ATP4A P20648 1/20 0.35
ATP4B P51164 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11018472 1.00 NPC1 (0.39) NPC1RAB9ASPHK2SPHK1ALDH1A1
SCHEMBL11018492 0.92 SPHK2 (0.43) NPC1RAB9ASPHK2SPHK1ALDH1A1
SCHEMBL11019370 0.92 SPHK2 (0.43) NPC1RAB9ASPHK2SPHK1ALDH1A1
SCHEMBL11018499 0.80 ALDH1A1 (0.43) NPC1RAB9ASPHK2SPHK1ALDH1A1
SCHEMBL11023485 0.78 NPSR1 (0.42) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL11017240 0.78 ALDH1A1 (0.38) NPC1RAB9ASPHK2SPHK1ALDH1A1
SCHEMBL11016752 0.77 FAAH (0.38) ALDH1A1NPSR1
SCHEMBL9811004 0.77 L3MBTL1 (0.37) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL11018442 0.77 FAAH (0.38) ALDH1A1NPSR1
SCHEMBL11020176 0.76 NPSR1 (0.40) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed