Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581085 | 0.98 | TSHR (0.44) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL15705449 | 0.93 | MEN1 (0.33) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL16367157 | 0.92 | HTT (0.50) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL3503366 | 0.91 | TSHR (0.33) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL3214360 | 0.89 | ALDH1A1 (0.33) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL3893505 | 0.89 | TSHR (0.34) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL21440327 | 0.89 | TSHR (0.44) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL11021775 | 0.89 | ALDH1A1 (0.33) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL17991841 | 0.89 | TSHR (0.32) | TSHR | |
| SCHEMBL28198125 | 0.86 | HTT (0.44) | TSHRCYP3A4MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160988-A2 | Stable silica-based ether bonded phases for biopolymer separations | BECKMAN INSTRUMENTS, INC. (US) | 1985-11-13 | — | — | EP | disclosed |