Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019407 | 1.00 | PPARG (0.56) | PPARGPPARAHRH3MAPTL3MBTL1 | |
| Butane SCHEMBL11296686 | 0.94 | MAPT (0.52) | PPARGPPARAHRH3MAPTL3MBTL1 | |
| SCHEMBL7433512 | 0.87 | TDP1 (0.62) | PPARGPPARAHRH3MAPTL3MBTL1 | |
| SCHEMBL7434198 | 0.87 | TDP1 (0.62) | PPARGPPARAHRH3MAPTL3MBTL1 | |
| SCHEMBL14097351 | 0.85 | NR5A1 (0.56) | MAPTL3MBTL1MEN1KMT2ACRHBP | |
| SCHEMBL5508343 | 0.84 | TDP1 (0.61) | PPARGPPARAMAPTL3MBTL1CRHBP | |
| SCHEMBL4756791 | 0.84 | TDP1 (0.61) | PPARGPPARAMAPTL3MBTL1CRHBP | |
| SCHEMBL5883644 | 0.83 | MEN1 (0.69) | HRH3MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7437760 | 0.83 | MEN1 (0.69) | HRH3MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL11294732 | 0.83 | MAPT (0.46) | PPARGPPARAHRH3MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |