Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | CRHBP | P24387 | 1/20 | 0.66 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437760 | 1.00 | MEN1 (0.69) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL7434198 | 0.94 | TDP1 (0.62) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL7433512 | 0.94 | TDP1 (0.62) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL11566016 | 0.93 | MEN1 (0.60) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL14097352 | 0.87 | MEN1 (0.71) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL7432275 | 0.87 | MEN1 (0.91) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL9469795 | 0.86 | MEN1 (0.69) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL7571535 | 0.85 | TDP1 (0.88) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL8080157 | 0.85 | TDP1 (0.88) | MEN1KMT2AL3MBTL1MAPTCRHBP | |
| SCHEMBL11022539 | 0.85 | TDP1 (0.88) | MEN1KMT2AL3MBTL1MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078543-B2 | Methods for producing oxirane carboxylic acids and derivatives thereof | MEDIGENE AKTIENGESELLSCHAFT (DE) | 2006-07-18 | — | — | US | disclosed |
| US-20040236103-A1 | Methods for producing oxirane carboxylic acids and derivatives thereof | MEDIGENE AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| US-4933365-A | ANTIFLAMMATORY AGENTS, ANTIALLERGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| WO-1989005142-A1 | PHOSPHOLIPASE A2 INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-06-15 | — | — | WO | disclosed |
| US-4788304-A | ANTIALLERGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236103-A1 | Methods for producing oxirane carboxylic acids and derivatives thereof | ACSL5, HSD17B12, COASY | MEN1 2746/4885KMT2A 2177/4885L3MBTL1 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.