Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434198 | 1.00 | TDP1 (0.62) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7437760 | 0.94 | MEN1 (0.69) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL5883644 | 0.94 | MEN1 (0.69) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL11566016 | 0.91 | MEN1 (0.60) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7432338 | 0.87 | MEN1 (0.81) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| Butane SCHEMBL11296686 | 0.87 | MAPT (0.52) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7429680 | 0.87 | TDP1 (0.81) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL11019407 | 0.87 | PPARG (0.56) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL11020355 | 0.87 | PPARG (0.56) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7434380 | 0.86 | TDP1 (0.83) | TDP1MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933365-A | ANTIFLAMMATORY AGENTS, ANTIALLERGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| WO-1989005142-A1 | PHOSPHOLIPASE A2 INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-06-15 | — | — | WO | disclosed |
| US-4788304-A | ANTIALLERGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |