Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020885 | 0.88 | PDE3A (0.54) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL11018063 | 0.85 | NPC1 (0.47) | HPGDKDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL11016904 | 0.85 | CRHBP (0.50) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL7381624 | 0.84 | KDM4E (0.57) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL11023628 | 0.82 | KDM4E (0.44) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL11021626 | 0.81 | ALDH1A1 (0.42) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL11021708 | 0.81 | HPGD (0.42) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL11019327 | 0.80 | KDM4E (0.48) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL11023428 | 0.80 | ALDH1A1 (0.45) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL11022101 | 0.79 | KDM4E (0.50) | HPGDKDM4EALDH1A1GALR3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |