Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632073 | 0.94 | MEN1 (0.62) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL29378094 | 0.92 | MEN1 (0.66) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL17697643 | 0.92 | MEN1 (0.66) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL18231622 | 0.87 | MEN1 (0.60) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL28986013 | 0.86 | MEN1 (0.62) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL2939502 | 0.85 | MEN1 (0.54) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL11797236 | 0.83 | EGFR (0.84) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL11022631 | 0.83 | TP53 (0.67) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL3430379 | 0.83 | MEN1 (0.51) | MEN1KMT2ACA1CA2TP53 | |
| SCHEMBL8382011 | 0.82 | MEN1 (0.84) | MEN1KMT2ATSHREGFRPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831862-B | Chiral bridged axial chiral monophosphine ligand and preparation method thereof | 中山大学 | 2021-01-15 | — | — | CN | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |