Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | EGFR | P00533 | 1/20 | 0.81 |
| ▸ | PIM1 | P11309 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAOA | P21397 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | ELANE | P08246 | 10/20 | 0.68 |
| ▸ | P4HB | P07237 | 1/20 | 0.58 |
| ▸ | CTSG | P08311 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797236 | 0.95 | EGFR (0.84) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL7786291 | 0.91 | MEN1 (1.00) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL11528272 | 0.90 | EGFR (1.00) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL8947495 | 0.89 | EGFR (0.73) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL16226264 | 0.85 | ELANE (0.73) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL16225768 | 0.85 | EGFR (0.64) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL8930315 | 0.85 | MAPT (0.73) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL16226324 | 0.85 | ALDH1A1 (0.69) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL5146135 | 0.84 | SMN1; SMN2 (0.69) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL3417492 | 0.83 | EGFR (0.76) | MEN1KMT2AEGFRPIM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178411-A | Small molecular probe for detecting p53 dysfunction and preparation method and application thereof | 山西大学 | 2023-05-30 | — | — | CN | disclosed |
| US-5922891-A | ANTI-INFLAMMATORY AGENTS WHICH INHIBIT LIPOXYGENASE PATHWAYS AND THERFORE PROLIFERATIVE ACTIVITY OF PRODUCTS OF THE PATHWAYS; SUPPRESSION OF IRON-DEPENDENT GENERATION OF OXYGEN FREE RADICALS, TREATMENT OF PSORIASIS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1999-07-13 | — | — | US | disclosed |
| WO-1996040623-A1 | 2-SUBSTITUTED 1,8-DIHYDROXY-9(10H)-ANTRACENONE AS PROLIFERATION AND 5-LIPOXYGENASE INHIBITORS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5053431-A | Antitumor-anticarcinogenic agents | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-10-01 | — | — | US | disclosed |
| WO-1990008759-A1 | DERIVATIVES OF CHRYSOPHANOL | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-08-09 | — | — | WO | disclosed |