Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021228 | 0.93 | AMY1A (0.54) | AMY1ASNCANPBWR1MEN1KMT2A | |
| SCHEMBL11020385 | 0.91 | AMY1A (0.50) | AMY1ASNCANPBWR1MEN1KMT2A | |
| SCHEMBL11020391 | 0.84 | AMY1A (0.60) | AMY1ANPBWR1MEN1KMT2ALMNA | |
| SCHEMBL11017854 | 0.83 | MAOB (0.43) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL11018593 | 0.82 | TP53 (0.46) | LMNAMAPTNPC1RAB9ANFKB1 | |
| SCHEMBL11018823 | 0.82 | TOP1 (0.40) | LMNAMAPTNPC1RAB9ANFKB1 | |
| SCHEMBL11018199 | 0.81 | CHEK2 (0.51) | CHEK2 | |
| SCHEMBL11018034 | 0.80 | RHEB (0.39) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL9634582 | 0.79 | PDE5A (0.40) | LMNAMAPTNPC1RAB9ANFKB1 | |
| SCHEMBL10736446 | 0.79 | TOP1 (0.41) | LMNAMAPTNPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |