Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018459 | 0.94 | RAB9A (0.52) | RAB9ANPC1HPGDTSHRMAOB | |
| SCHEMBL11018675 | 0.91 | RAB9A (0.52) | RAB9ANPC1HPGDTSHRMAOB | |
| SCHEMBL11024159 | 0.87 | MAOB (0.48) | RAB9ANPC1HPGDTSHRMAOB | |
| SCHEMBL11020036 | 0.86 | MAOB (0.50) | RAB9ANPC1HPGDTSHRMAOB | |
| SCHEMBL11022908 | 0.83 | MAOB (0.56) | RAB9ANPC1HPGDTSHRMAOB | |
| SCHEMBL10676138 | 0.82 | RAB9A (0.58) | RAB9ANPC1HPGDMAOBBCHE | |
| SCHEMBL11021740 | 0.82 | RAB9A (0.64) | RAB9ANPC1HPGDTSHRMAOB | |
| SCHEMBL11019981 | 0.81 | KDM4E (0.65) | ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL15924331 | 0.81 | RAB9A (0.58) | RAB9ANPC1HPGDTSHRMAOB | |
| SCHEMBL11022638 | 0.81 | L3MBTL1 (0.44) | NPC1HPGDMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |