Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933956 | 0.82 | CYP1A2 (0.50) | CYP1A2SIGMAR1METAP1EPHX1 | |
| SCHEMBL8280559 | 0.78 | CYP1A2 (0.52) | CYP1A2SIGMAR1METAP1 | |
| SCHEMBL13460092 | 0.78 | CYP1A2 (0.52) | CYP1A2SIGMAR1METAP1 | |
| SCHEMBL16934021 | 0.76 | SIGMAR1 (0.50) | CYP1A2SIGMAR1METAP1EPHX1 | |
| SCHEMBL16934012 | 0.74 | SIGMAR1 (0.54) | CYP1A2SIGMAR1METAP1EPHX1 | |
| SCHEMBL9253751 | 0.73 | CYP1A2 (0.56) | CYP1A2SIGMAR1METAP1 | |
| SCHEMBL671383 | 0.73 | CYP1A2 (0.50) | CYP1A2SIGMAR1METAP1EPHX1 | |
| SCHEMBL16933914 | 0.73 | CYP1A2 (0.50) | CYP1A2SIGMAR1METAP1EPHX1 | |
| SCHEMBL16933712 | 0.73 | CYP1A2 (0.50) | CYP1A2SIGMAR1METAP1EPHX1 | |
| SCHEMBL1524631 | 0.73 | CYP1A2 (0.56) | CYP1A2SIGMAR1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159784-A1 | Carbacyclin analogues | THE UPJOHN COMPANY (US) | 1985-10-30 | — | — | EP | disclosed |