Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791289 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL6230097 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL7069579 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL3805670 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL20377261 | 0.97 | — | — | |
| SCHEMBL2362985 | 0.88 | — | — | |
| 1-Bromobutane SCHEMBL1249759 | 0.79 | DNM1 (0.35) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL27674294 | 0.78 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL10900080 | 0.78 | LMNA (0.46) | LMNA | |
| SCHEMBL27248836 | 0.77 | LCK (0.43) | LCKPPARDZDHHC20ZDHHC2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |