Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840678 | 0.85 | ALB (0.50) | ALBKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL17797891 | 0.80 | ALDH1A1 (0.46) | KDM4EHPGDHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL16892295 | 0.80 | CES2 (0.36) | CES2CES1ALDH1A1GAAMEN1 | |
| SCHEMBL8323980 | 0.79 | ALB (0.47) | ALBKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL17294876 | 0.77 | ALB (0.57) | ALBKDM4EHPGDHSD17B10SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27753081 | 0.75 | NOTUM (0.41) | ALBKDM4EHPGDHSD17B10CES2 | |
| SCHEMBL27732580 | 0.75 | CES2 (0.47) | ALBKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL27446530 | 0.74 | KDM4E (0.47) | ALBKDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1834432 | 0.72 | POLB (0.47) | ALBKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL3389839 | 0.72 | ALDH1A1 (0.52) | ALBKDM4EHPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028277-B1 | SUBSTITUTED DIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM AND METHOD OF COMBATING WEEDS | ROHM AND HAAS COMPANY (US) | 1985-01-23 | — | — | EP | disclosed |
| EP-0028277-A1 | Substituted diphenyl ethers, herbicidal compositions containing them and method of combating weeds | ROHM AND HAAS COMPANY (US) | 1981-05-13 | — | — | EP | disclosed |