Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.52 |
| ▸ | HTR3B | O95264 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022355 | 1.00 | HTR3E (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL861925 | 0.84 | MAPT (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8964884 | 0.84 | MAPT (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5709717 | 0.81 | NPC1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL18434376 | 0.78 | POLB (0.51) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11045379 | 0.75 | MAPT (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29820042 | 0.73 | ALDH1A1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29820211 | 0.73 | ALDH1A1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1405328 | 0.73 | ALDH1A1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1405330 | 0.73 | ALDH1A1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062200-B1 | DISAZO DYESTUFFS | BASF Aktiengesellschaft (DE) | 1985-01-23 | — | — | EP | disclosed |
| EP-0062200-A1 | Disazo dyestuffs | BASF Aktiengesellschaft (DE) | 1982-10-13 | — | — | EP | disclosed |
| EP-0037465-A2 | Amino azo compounds | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |