Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739138 | 0.76 | ALOX5 (0.68) | ALOX5ALOX15MAPTLMNAPOLB | |
| SCHEMBL9739854 | 0.73 | ALOX5 (0.64) | ALOX5ALOX15MAPTLMNAPOLB | |
| SCHEMBL11460802 | 0.66 | NPSR1 (0.57) | MAPTLMNAPOLB | |
| SCHEMBL9742519 | 0.66 | ALOX5 (0.69) | ALOX5ALOX15 | |
| SCHEMBL9739591 | 0.65 | ALOX5 (1.00) | ALOX5ALOX15 | |
| SCHEMBL5202817 | 0.64 | GAA (0.66) | MAPTPOLB | |
| SCHEMBL9739535 | 0.63 | ALOX5 (0.59) | ALOX5ALOX15 | |
| SCHEMBL9739661 | 0.63 | ALOX5 (0.72) | ALOX5ALOX15 | |
| SCHEMBL6941063 | 0.63 | GAA (0.64) | MAPTLMNAPOLB | |
| SCHEMBL435444 | 0.63 | GAA (0.68) | MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165810-A2 | Benzofuran and benzothiophene derivatives, their use in inhibiting mammalian leukotriene biosynthesis, and pharmaceutical compositions containing these derivatives | MERCK FROSST CANADA INC. (CA) | 1985-12-27 | — | — | EP | disclosed |