Phenol

Phenol

SCHEMBL11022985

FCC(F)(F)C(F)(F)F.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
GLA P06280 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA9 Q16790 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ESR1 P03372 9/20 0.39
ESR2 Q92731 7/20 0.38
MMP3 P08254 1/20 0.37
BCL2L1 Q07817 1/20 0.37
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 1/20 0.35
CES1 P23141 2/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
LTA4H P09960 1/20 0.33
NR1H2 P55055 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28792079 1.00 CA12 (0.50) CA12CA1CA2GLACA3
Hydroquinone SCHEMBL7940837 0.88 ESR1 (0.48) CA12CA1CA2CA3CA4
SCHEMBL28706473 0.82 KIF11 (0.52) CA12CA1CA2CA3CA4
Biphenyl SCHEMBL8089799 0.81 KIF11 (0.46) TDP1MMP3BCL2L1ALDH1A1CYP3A4
4-Aminophenol SCHEMBL28952747 0.78 ALDH1A1 (0.54) CA3TDP1CA14ESR1ESR2
SCHEMBL28453756 0.78 HSD17B10 (0.41) CA12CA2CA3CA4TDP1
SCHEMBL9068924 0.78 PDK2 (0.34) ALDH1A1CES1LMNATSHRMEN1
Phenol SCHEMBL15956084 0.77 CA12 (0.73) CA12CA1CA2GLACA3
Phenol SCHEMBL28056367 0.75 CA12 (0.69) CA12CA1CA2GLACA3
SCHEMBL32838 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0092310-B1 BIS(HALOPHENYL)HEXAFLUOROPROPANES AND PROCESS FOR MAKING THE SAME Hughes Aircraft Company (US) 1985-07-24 EP claimed
CN-116445075-A Preparation method of low-refractive-index optical fiber coating 范伟 2023-07-18 CN disclosed