Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.58 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024671 | 1.00 | FOLH1 (0.58) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL9810164 | 0.97 | FOLH1 (0.53) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL9810168 | 0.97 | FOLH1 (0.53) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL9738061 | 0.88 | FOLH1 (0.60) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL9738069 | 0.88 | FOLH1 (0.60) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL6823763 | 0.84 | FOLH1 (0.58) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL9856603 | 0.83 | SIRT2 (0.52) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL6827646 | 0.83 | HTT (0.59) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL25453638 | 0.82 | CA1 (0.61) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL11758185 | 0.82 | HTT (0.58) | FOLH1MMP2MMP9SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088350-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0088350-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1983-09-14 | — | — | EP | disclosed |