Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810168 | 1.00 | FOLH1 (0.53) | FOLH1HTTMMP2MMP9CPB1 | |
| SCHEMBL11023043 | 0.97 | FOLH1 (0.58) | FOLH1HTTMMP2MMP9CPB1 | |
| SCHEMBL11024671 | 0.97 | FOLH1 (0.58) | FOLH1HTTMMP2MMP9CPB1 | |
| SCHEMBL23901494 | 0.85 | HTT (0.58) | FOLH1HTTMMP2MMP9CPB1 | |
| SCHEMBL9738061 | 0.85 | FOLH1 (0.60) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL9738069 | 0.85 | FOLH1 (0.60) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL3369452 | 0.81 | ACE (0.60) | ACELMNASMN1; SMN2 | |
| SCHEMBL497515 | 0.81 | ACE (0.60) | ACELMNASMN1; SMN2 | |
| SCHEMBL1221172 | 0.81 | ACE (0.60) | ACELMNASMN1; SMN2 | |
| SCHEMBL4669921 | 0.81 | ACE (0.60) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017567-A | Steroid antiinflammatory | SCHERING CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| US-4906635-A | Carboxyalkyl dipeptides as antiglaucoma agents | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4778795-A | Carboxyalkyl dipeptides as antiglaucoma agents | SCHERING CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| US-4616012-A | BENZOTHIADIZINYL AND QUINAZOLINYL DERIVATIVES | SCHERING CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |
| US-4559340-A | DIURETICS; GLAUCOMA | SCHERING CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |