SCHEMBL11023405

SCHEMBL11023405

O=C(O)Oc1ccc(CC(NOCc2ccccc2)C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.52
GPR34 Q9UPC5 3/20 0.48
KMT2A Q03164 1/20 0.47
FPR2 P25090 1/20 0.47
MME P08473 1/20 0.46
ACE P12821 1/20 0.46
CPA1 P15085 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
ITGB3 P05106 4/20 0.46
ITGA2B P08514 4/20 0.46
GPR132 Q9UNW8 1/20 0.45
PPARA Q07869 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130477 0.89 MME (0.51) PPARGFPR2MMEGPR132
SCHEMBL6130478 0.89 MME (0.51) PPARGFPR2MMEGPR132
SCHEMBL7211707 0.89 MME (0.51) PPARGFPR2MMEGPR132
SCHEMBL29664067 0.86 MME (0.56) PPARGMMEACE
SCHEMBL28216930 0.86 MME (0.56) PPARGMMEACE
SCHEMBL6800455 0.77 ITGB3 (0.65) ACEITGB3ITGA2BGPR132
SCHEMBL8078091 0.77 ACE (0.56) GPR34MMEACEGPR132
SCHEMBL2747735 0.76 PPARG (0.65) PPARGGPR34MMEACECPA1
SCHEMBL5507068 0.76 NPC1 (0.49) KMT2AMMEGPR132
SCHEMBL7004556 0.76 NPC1 (0.49) KMT2AMMEGPR132

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034052-B1 A RECORDING MEDIUM PROCESS SHIZAI CO. LTD. (JP) 1985-05-08 EP disclosed