Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078197 | 0.91 | ATM (0.53) | ACELMNA | |
| SCHEMBL7211707 | 0.87 | MME (0.51) | GPR132MMENPSR1 | |
| SCHEMBL6130478 | 0.87 | MME (0.51) | GPR132MMENPSR1 | |
| SCHEMBL6130477 | 0.87 | MME (0.51) | GPR132MMENPSR1 | |
| SCHEMBL8085158 | 0.82 | ITGB3 (0.60) | ACEECE1MME | |
| SCHEMBL2559773 | 0.82 | GAA (0.50) | ECE1MME | |
| SCHEMBL2559768 | 0.82 | GAA (0.50) | ECE1MME | |
| SCHEMBL9417473 | 0.81 | GPR34 (0.62) | ACEGPR132GPR34MMENOS2 | |
| SCHEMBL29664067 | 0.81 | MME (0.56) | ACEECE1MME | |
| SCHEMBL28216930 | 0.81 | MME (0.56) | ACEECE1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510552-B2 | Preparation process of alpha-aspartyl-L-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS (JP) | 2000-11-15 | — | — | EP | claimed |