SCHEMBL11023540

SCHEMBL11023540

C=CCSCC(O)CSCC=C

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TRPA1 O75762 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11879501 0.89 ALOX5 (0.42) ALOX5SMN1; SMN2TRPA1ALDH1A1CYP3A4
SCHEMBL5320940 0.87
SCHEMBL9374822 0.87 ALOX5 (0.46) ALOX5SMN1; SMN2TRPA1ALDH1A1CYP3A4
SCHEMBL11878098 0.87 ALOX5 (0.40) ALOX5SMN1; SMN2
SCHEMBL11883592 0.87 ALOX5 (0.40) ALOX5SMN1; SMN2
SCHEMBL5613863 0.85
SCHEMBL27615249 0.85
SCHEMBL11880486 0.85
SCHEMBL9768960 0.79
SCHEMBL11577679 0.79 ALOX5 (0.37) ALOX5SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0064020-B1 SYNERGISTIC ANTIOXIDANT MIXTURES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-06-19 EP claimed
EP-0064020-A1 Synergistic antioxidant mixtures THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-11-03 EP claimed
EP-0064020-B1 SYNERGISTIC ANTIOXIDANT MIXTURES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-06-19 EP disclosed
US-4370434-A PHENOLS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-01-25 US disclosed
US-4362887-A ESTERS, THIO, POLYPROPYLENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-12-07 US disclosed
EP-0064020-A1 Synergistic antioxidant mixtures THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-11-03 EP disclosed