⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11879501 | 0.96 | ALOX5 (0.42) | — | |
| SCHEMBL11023540 | 0.87 | ALOX5 (0.53) | — | |
| Diallyl Sulfide SCHEMBL9376569 | 0.85 | ALOX5 (0.58) | — | |
| SCHEMBL11881950 | 0.84 | CA1 (0.36) | — | |
| SCHEMBL9374822 | 0.81 | ALOX5 (0.46) | — | |
| SCHEMBL11878098 | 0.80 | ALOX5 (0.40) | — | |
| SCHEMBL5613863 | 0.79 | — | — | |
| SCHEMBL11880486 | 0.79 | — | — | |
| SCHEMBL27615249 | 0.79 | — | — | |
| SCHEMBL890790 | 0.76 | LMNA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011710-A1 | METHODS OF TREATING VIRAL INFECTIONS | CHIMERIX, INC. (US) | 2011-01-27 | — | — | WO | claimed |
| EP-0043472-A1 | 3-Hydrocarbylthio-2-acyloxypropyl 2-trimethylammonioethyl phosphates, process for producing the same and pharmaceutical preparations containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-01-13 | — | — | EP | claimed |
| EP-2841162-A1 | A METHOD OF MITIGATING VIRUS ASSOCIATED END-ORGAN DAMAGE | Chimerix, Inc. (US) | 2015-03-04 | — | — | EP | disclosed |
| EP-2770834-A1 | HEXADECYLOXYPROPYL CIDOFOVIR FOR THE TREATMENT OF DOUBLE-STRANDED DNA VIRUS INFECTION | Chimerix, Inc. (US) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013163509-A1 | A METHOD OF MITIGATING VIRUS ASSOCIATED END-ORGAN DAMAGE | CHIMERIX, INC. (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013062119-A1 | CURABLE COMPOSITION | DOW CORNING TORAY CO., LTD. (JP) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013063436-A1 | HEXADECYLOXYPROPYL CIDOFOVIR FOR THE TREATMENT OF DOUBLE-STRANDED DNA VIRUS INFECTION | CHIMERIX, INC. (US) | 2013-05-02 | — | — | WO | disclosed |
| EP-1868628-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS | Chimerix, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006110655-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS | CHIMERIX, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-5851548-A | Liposomes containing cationic lipids and vitamin D | GEN-PROBE INCORPORATED (US) | 1998-12-22 | — | — | US | disclosed |
| US-5759519-A | Method for the intracellular delivery of biomolecules using thiocationic lipids | GEN-PROBE INCORPORATED (US) | 1998-06-02 | — | — | US | disclosed |
| US-5711964-A | CELLULAR METABOLISM AND CATIONIC LIPIDS | UNITED STATES OF AMERICA (US) | 1998-01-27 | — | — | US | disclosed |
| WO-1996040627-A2 | THIOCATIONIC LIPIDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | GEN-PROBE INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0747351-A2 | Thiocationic lipids, pharmaceutical compositions and methods of use thereof | GEN-PROBE INCORPORATED (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0043472-B1 | 3-HYDROCARBYLTHIO-2-ACYLOXYPROPYL 2-TRIMETHYLAMMONIOETHYL PHOSPHATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1983-07-20 | — | — | EP | disclosed |
| EP-0043472-A1 | 3-Hydrocarbylthio-2-acyloxypropyl 2-trimethylammonioethyl phosphates, process for producing the same and pharmaceutical preparations containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-01-13 | — | — | EP | disclosed |
| US-4087466-A | NONIONIC SURFACTANTS | L'OREAL (FR) | 1978-05-02 | — | — | US | disclosed |
| US-4058629-A | Polyhydroxyl monosulfoxide shampoo compositions | L'OREAL (FR) | 1977-11-15 | — | — | US | disclosed |
| US-3984480-A | Polyhydroxyl monosulfoxide surfactant | L'OREAL (FR) | 1976-10-05 | — | — | US | disclosed |
| US-3966398-A | Hair dyeing composition containing a non-ionic surfactant | L'OREAL (FR) | 1976-06-29 | — | — | US | disclosed |