⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19397172 | 1.00 | — | — | |
| SCHEMBL15894136 | 1.00 | — | — | |
| SCHEMBL9921199 | 1.00 | — | — | |
| SCHEMBL26031968 | 0.88 | PDK1 (0.32) | — | |
| SCHEMBL12292409 | 0.88 | PDK1 (0.32) | — | |
| SCHEMBL26025540 | 0.88 | PDK1 (0.32) | — | |
| SCHEMBL24996781 | 0.86 | — | — | |
| SCHEMBL25707028 | 0.83 | — | — | |
| SCHEMBL13045067 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL21722594 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330246-A1 | COMPOSITIONS AND METHODS OF TREATING POMPE DISEASE | AVIDITY BIOSCIENCES, INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230287420-A1 | COMPOSITIONS AND METHODS OF TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | AVIDITY BIOSCIENCES, INC. | 2023-09-14 | — | — | US | disclosed |
| US-20230279395-A1 | COMPOSITIONS AND METHODS OF TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | AVIDITY BIOSCIENCES, INC. | 2023-09-07 | — | — | US | disclosed |
| US-10982007-B2 | Detection of a posttranslationally modified polypeptide by a bivalent binding agent | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-20200207874-A1 | POLYPEPTIDE-POLYNUCLEOTIDE-COMPLEX AND ITS USE IN TARGETED EFFECTOR MOIETY DELIVERY | HOFFMANN-LA ROCHE INC. (US) | 2020-07-02 | — | — | US | disclosed |
| US-10633460-B2 | Binding agent | ROCHE DIAGNOSTIC OPERATIONS, INC. (US) | 2020-04-28 | — | — | US | disclosed |
| EP-2659275-B1 | DETECTION OF A POLYPEPTIDE DIMER BY A BIVALENT BINDING AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 2017-11-22 | — | — | EP | disclosed |
| US-20170275381-A1 | DETECTION OF A POSTTRANSLATIONALLY MODIFIED POLYPEPTIDE BY A BIVALENT BINDING AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 2017-09-28 | — | — | US | disclosed |
| US-20170275381-A1 | DETECTION OF A POSTTRANSLATIONALLY MODIFIED POLYPEPTIDE BY A BIVALENT BINDING AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 2017-09-28 | — | — | US | disclosed |
| US-20170275380-A1 | DETECTION OF A POLYPEPTIDE DIMER BY A BIVALENT BINDING AGENT | ROCHE DIAGNOSTICS OPERATIONS INC (US) | 2017-09-28 | — | — | US | disclosed |
| US-7485442-B2 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-20080206265-A1 | SYNERGISTIC TREATMENT OF CANCER USING IMMUNOMERS IN CONJUNCTION WITH CHEMOTHERAPEUTIC AGENTS | IDERA PHARMACEUTICALS, INC. | 2008-08-28 | — | — | US | disclosed |
| US-7407944-B2 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends | IDERA PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20080152662-A1 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends | IDERA PHARMACEUTICALS, INC. | 2008-06-26 | — | — | US | disclosed |
| US-7276489-B2 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends | IDERA PHARMACEUTICALS, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20070173469-A1 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends | HYBRIDON, INC. | 2007-07-26 | — | — | US | disclosed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |