Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.65 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019878 | 0.81 | CYP2A13 (0.55) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL922732 | 0.79 | CTSB (1.00) | CTSBKCNJ1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11018569 | 0.79 | KDM4E (0.53) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10692345 | 0.78 | CTSB (0.97) | CTSBKCNJ1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10692339 | 0.78 | CTSB (0.97) | CTSBKCNJ1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11019683 | 0.77 | CYP2A13 (0.51) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL17979926 | 0.76 | CTSB (0.71) | CTSBKCNJ1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15000189 | 0.76 | CTSB (0.71) | CTSBKCNJ1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL521635 | 0.76 | LMNA (0.71) | CTSBKCNJ1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL922716 | 0.76 | KCNJ1 (0.74) | CTSBKCNJ1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | disclosed |