3,4,5-Trimethoxybenzoic Acid

3,4,5-Trimethoxybenzoic Acid

SCHEMBL11023602

COc1cc(C(=O)O)cc(OC)c1OC.[NaH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 5/20 0.75
CA12 O43570 2/20 0.67
CA1 P00915 2/20 0.67
CA2 P00918 2/20 0.67
CA4 P22748 2/20 0.67
CA6 P23280 2/20 0.67
CA7 P43166 2/20 0.67
CA9 Q16790 2/20 0.67
CA14 Q9ULX7 2/20 0.67
CA3 P07451 1/20 0.67
PKM P14618 1/20 0.67
CA5A P35218 1/20 0.67
CA5B Q9Y2D0 1/20 0.67
PTGS2 P35354 1/20 0.62
HTT P42858 1/20 0.55
CNR2 P34972 1/20 0.55
TUBB4A P04350 1/20 0.55
TUBB P07437 1/20 0.55
TUBA3C P0DPH7 1/20 0.55
TUBA1B P68363 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 0.98 TPMT (0.78) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL9739818 0.96 TPMT (0.75) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL4080846 0.96 TPMT (0.75) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL10838612 0.96 TPMT (0.75) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL9427206 0.94 TPMT (0.72) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL10876063 0.88 TPMT (0.66) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL10876055 0.88 TPMT (0.66) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL6559147 0.88 TPMT (0.71) TPMTCA12CA1CA2CA4
SCHEMBL17655663 0.88 TPMT (0.70) TPMTCA12CA1CA2CA4
SCHEMBL15673397 0.87 TSHR (0.65) TPMTCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0160760-A1 Preparation of trimethoxybenzoate esters and trimethoxybenzoic acid Mallinckrodt, Inc. (a Delaware corporation) (US) 1985-11-13 EP disclosed
US-4471134-A Preparation of trimethoxybenzoate esters and trimethoxybenzoic acid MALLINCKRODT, INC. (US) 1984-09-11 US disclosed
US-4055653-A Sulfur containing trialkoxybenzoylamino carboxylic acids DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-10-25 US disclosed
US-4010193-A (ALKYLAMINO)ALKYL SUBSTITUTED BENZOATES, LOCAL ANESTHETIC, ANTIFIBRILLATORY, ANTIARRHYTHMIAL CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) 1977-03-01 US disclosed
US-3981910-A Sulfur containing trialkoxybenzoylamino carboxylic acids DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-09-21 US disclosed