3,4,5-Trimethoxybenzoic Acid

3,4,5-Trimethoxybenzoic Acid

SCHEMBL6592

COc1cc(C(=O)O)cc(OC)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 5/20 0.78
CA12 O43570 2/20 0.69
CA1 P00915 2/20 0.69
CA2 P00918 2/20 0.69
CA4 P22748 2/20 0.69
CA6 P23280 2/20 0.69
CA7 P43166 2/20 0.69
CA9 Q16790 2/20 0.69
CA14 Q9ULX7 2/20 0.69
CA3 P07451 1/20 0.69
PKM P14618 1/20 0.69
CA5A P35218 1/20 0.69
CA5B Q9Y2D0 1/20 0.69
PTGS2 P35354 1/20 0.64
HTT P42858 1/20 0.57
CNR2 P34972 1/20 0.56
TUBB4A P04350 1/20 0.56
TUBB P07437 1/20 0.56
TUBA3C P0DPH7 1/20 0.56
TUBA1B P68363 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4,5-Trimethoxybenzoic Acid SCHEMBL11023602 0.98 TPMT (0.75) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL4080846 0.98 TPMT (0.75) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL9739818 0.98 TPMT (0.75) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL10838612 0.98 TPMT (0.75) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL9427206 0.96 TPMT (0.72) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL10876063 0.90 TPMT (0.66) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL6559147 0.90 TPMT (0.71) TPMTCA12CA1CA2CA4
3,4,5-Trimethoxybenzoic Acid SCHEMBL10876055 0.90 TPMT (0.66) TPMTCA12CA1CA2CA4
SCHEMBL17655663 0.90 TPMT (0.70) TPMTCA12CA1CA2CA4
SCHEMBL15673397 0.89 TSHR (0.65) TPMTCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2840 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
WO-2025202864-A1 ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER iTeos Belgium SA (BE) 2025-10-02 WO claimed
WO-2025126110-A1 ENT1 INHIBITORS IN COMBINATION WITH BISPECIFIC ANTIBODIES iTeos Belgium SA (BE) 2025-06-19 WO claimed
CN-120118086-A 1, 7-Disubstituted pyrrolo [1,2-a ] pyrazine compound and preparation method and application thereof 沈阳药科大学 2025-06-10 CN claimed
EP-4559009-A2 PARTICLES Life Technologies AS (NO) 2025-05-28 EP claimed
WO-2025104613-A1 ENT1 INHIBITORS IN COMBINATION WITH CHECKPOINT INHIBITORS iTeos Belgium SA (BE) 2025-05-22 WO claimed
CN-119874466-A N, N-dimethylamide compound and synthesis method thereof 海南大学 2025-04-25 CN claimed
CN-119698673-A Particles 生命技术股份公司 2025-03-25 CN claimed
US-20250049676-A1 ANTIMICROBIAL SYSTEM WITH INDOLE ALKALOID AND PHENOLIC ACID AND COMPOSITIONS COMPRISING THEM CONOPCO, INC., D/B/A UNILEVER (US) 2025-02-13 US claimed
US-20240400581-A1 Process for Preparing a Macrocyclic Compound Having ENT1 Inhibiting Activity iTeos Belgium SA (BE) 2024-12-05 US claimed
WO-1986004582-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1986-08-14 WO claimed
EP-0160760-A1 Preparation of trimethoxybenzoate esters and trimethoxybenzoic acid Mallinckrodt, Inc. (a Delaware corporation) (US) 1985-11-13 EP claimed
US-4501920-A Preparation of trimethoxybenzoate salts and trimethoxybenzoic acid MALLINCKRODT, INC. (US) 1985-02-26 US claimed
US-4471134-A Preparation of trimethoxybenzoate esters and trimethoxybenzoic acid MALLINCKRODT, INC. (US) 1984-09-11 US claimed
US-4469820-A Polyurethane prepared from a polyoxyalkylene containing an oxidation inhibiting amount of a benzoic acid salt BASF WYANDOTTE CORPORATION (US) 1984-09-04 US claimed
US-4426300-A Oxidation stable polyoxyalkylenes containing salts of benzoic acid derivatives BASF WYANDOTTE CORPORATION (US) 1984-01-17 US claimed
US-4259332-A ANTILIPEMIC, CHOLERETIC, ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC LABORATORIO CHIMICO FARMACEUTICO CAUSYTH S.P.A. (IT) 1981-03-31 US claimed
US-4191841-A DEMETHYLATION USING AN ALKALI HYDROXIDE AND ETHYLENE GLYCOL SOCIETE FRANCAISE HOECHST (FR) 1980-03-04 US claimed
US-4123534-A VIGILANCE INCREASING AGENTS Wulfing, Johann W. (DE) 1978-10-31 US claimed
US-4005145-A ISOMERIZATION OF A,B-UNSATURATED OXO COMPOUNDS TO B,G-ISOMER HOFFMANN-LA ROCHE INC. (US) 1977-01-25 US claimed