3,4,5-Trimethoxybenzoic Acid

3,4,5-Trimethoxybenzoic Acid

SCHEMBL6559147

COc1cc(C(=O)O)cc(OC)c1OC.O=C(O)c1cc(O)cc(O)c1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 5/20 0.71
CA12 O43570 3/20 0.63
CA1 P00915 3/20 0.63
CA2 P00918 3/20 0.63
CA7 P43166 3/20 0.63
CA9 Q16790 3/20 0.63
CA14 Q9ULX7 3/20 0.63
CA4 P22748 2/20 0.63
CA6 P23280 2/20 0.63
CA3 P07451 1/20 0.63
PKM P14618 1/20 0.63
CA5A P35218 1/20 0.63
CA5B Q9Y2D0 1/20 0.63
MAPT P10636 2/20 0.61
CYP3A4 P08684 1/20 0.61
PTGS2 P35354 1/20 0.59
HTT P42858 1/20 0.53
TUBB4A P04350 2/20 0.50
TUBB P07437 2/20 0.50
TUBA3C P0DPH7 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 0.90 TPMT (0.78) TPMTCA12CA1CA2CA7
3,4,5-Trimethoxybenzoic Acid SCHEMBL4080846 0.88 TPMT (0.75) TPMTCA12CA1CA2CA7
3,4,5-Trimethoxybenzoic Acid SCHEMBL11023602 0.88 TPMT (0.75) TPMTCA12CA1CA2CA7
3,4,5-Trimethoxybenzoic Acid SCHEMBL10838612 0.88 TPMT (0.75) TPMTCA12CA1CA2CA7
3,4,5-Trimethoxybenzoic Acid SCHEMBL9739818 0.88 TPMT (0.75) TPMTCA12CA1CA2CA7
3,4,5-Trimethoxybenzoic Acid SCHEMBL9427206 0.86 TPMT (0.72) TPMTCA12CA1CA2CA7
3,4,5-Trimethoxybenzoic Acid SCHEMBL28170224 0.86 TPMT (0.68) TPMTCA12CA1CA2CA7
SCHEMBL13064970 0.85 MEN1 (0.62) TPMTCA12CA1CA2CA7
SCHEMBL6559151 0.84 MAPT (0.59) TPMTCA12CA1CA2CA7
SCHEMBL30240911 0.83 TPMT (1.00) TPMTCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404372-A1 PHARMACEUTICAL FORMULATIONS AND LIGANDS FOR USE THEREIN; MIMETICS FOR UEA-1 Sarlan, Ltd. (BM) 2004-04-07 EP disclosed
WO-2003004062-A9 PHARMACEUTICAL FORMULATIONS AND LIGANDS FOR USE THEREIN; MIMETICS FOR UEA-1 SARLAN LTD 2003-04-10 WO disclosed
WO-2003004062-A1 PHARMACEUTICAL FORMULATIONS AND LIGANDS FOR USE THEREIN; MIMETICS FOR UEA-1 SARLAN, LTD. (BM) 2003-01-16 WO disclosed