Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580528 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CA2NPSR1 | |
| SCHEMBL9778093 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CA2NPSR1 | |
| SCHEMBL46416 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CA2NPSR1 | |
| SCHEMBL8372853 | 0.83 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL221388 | 0.82 | — | — | |
| SCHEMBL4965571 | 0.82 | CA2 (0.47) | ALDH1A1CA2NPSR1TMEM97SIGMAR1 | |
| SCHEMBL220145 | 0.82 | — | — | |
| SCHEMBL23556 | 0.82 | — | — | |
| Ethylene Glycol SCHEMBL11341777 | 0.81 | CA2 (0.39) | ALDH1A1CA2NPSR1TMEM97SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL21775798 | 0.80 | CA2 (0.46) | ALDH1A1CA2NPSR1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030807-B1 | SHAPED BIOMEDICAL ARTICLES MADE OF POLYSILOXANE POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 1985-06-19 | — | — | EP | disclosed |
| EP-0035080-B1 | SHAPED BIOMEDICAL ARTICLES FORMED FROM POLYSILOXANE POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 1984-08-15 | — | — | EP | disclosed |
| EP-0035080-A1 | Shaped biomedical articles formed from polysiloxane polymers | BAUSCH & LOMB INCORPORATED (US) | 1981-09-09 | — | — | EP | disclosed |
| EP-0030807-A1 | Shaped biomedical articles made of polysiloxane polymers | BAUSCH & LOMB INCORPORATED (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4260725-A | Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains | BAUSCH & LOMB INCORPORATED (US) | 1981-04-07 | — | — | US | disclosed |
| US-4259467-A | Hydrophilic contact lens made from polysiloxanes containing hydrophilic sidechains | BAUSCH & LOMB INCORPORATED (US) | 1981-03-31 | — | — | US | disclosed |