Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029166 | 0.83 | HDAC6 (0.52) | MAPK14HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11025263 | 0.83 | HDAC6 (0.52) | MAPK14HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11116772 | 0.82 | HDAC3 (0.53) | MAPK14HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11022766 | 0.79 | HDAC6 (0.51) | MAPK14HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11118913 | 0.78 | ERCC1 (0.49) | HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL140390 | 0.77 | EGFR (0.53) | MAPK14HDAC6MEN1KMT2ACA2 | |
| SCHEMBL6248105 | 0.77 | EGFR (0.53) | MAPK14HDAC6MEN1KMT2ACA2 | |
| SCHEMBL5532830 | 0.74 | AR (0.52) | MAPK14HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5531673 | 0.74 | AR (0.56) | MAPK14HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5532824 | 0.74 | AR (0.52) | MAPK14HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059108-B1 | DERIVATIVES OF DIHYDROXYBENZOIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-14 | — | — | EP | claimed |