Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025263 | 1.00 | HDAC6 (0.52) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11022766 | 0.88 | HDAC6 (0.51) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11023693 | 0.83 | MAPK14 (0.47) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11041409 | 0.81 | HDAC3 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7487285 | 0.81 | HDAC3 (0.64) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8598520 | 0.81 | HDAC3 (0.64) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL140390 | 0.80 | EGFR (0.53) | HDAC6MAPK14MEN1KMT2ACA2 | |
| SCHEMBL6248105 | 0.80 | EGFR (0.53) | HDAC6MAPK14MEN1KMT2ACA2 | |
| SCHEMBL11028825 | 0.80 | KDM4E (0.50) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20869041 | 0.79 | MAPK14 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059108-B1 | DERIVATIVES OF DIHYDROXYBENZOIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-14 | — | — | EP | claimed |
| EP-0059108-A1 | Derivatives of dihydroxybenzoic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-09-01 | — | — | EP | claimed |
| JP-57140754-A | — | — | None | — | — | JP | disclosed |
| EP-0059108-B1 | DERIVATIVES OF DIHYDROXYBENZOIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4409240-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS, BRONCHODILATOR, AND ANTIARTHRITIC AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0059108-A1 | Derivatives of dihydroxybenzoic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-09-01 | — | — | EP | disclosed |
| JP-S57140754-A | DIHYDROXYBENZOIC ACID DERIVATIVE AND PHYSIOLOGICALLY ACTIVE PREPARATION CONTAINING THE SAME | KUREHA CHEM IND CO LTD | 1982-08-31 | — | — | JP | disclosed |