Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 11/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 11/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117449 | 0.82 | ERCC1 (0.52) | ERCC1ERCC4HDAC1MEN1KMT2A | |
| SCHEMBL11117447 | 0.82 | ERCC1 (0.52) | ERCC1ERCC4HDAC1MEN1KMT2A | |
| SCHEMBL11023693 | 0.78 | MAPK14 (0.47) | HDAC1MEN1KMT2AHDAC6 | |
| SCHEMBL11116357 | 0.77 | MEN1 (0.49) | MEN1KMT2AKDM4ETSHRHIF1A | |
| SCHEMBL140023 | 0.73 | ERCC1 (0.57) | ERCC1ERCC4HDAC1GAAHDAC6 | |
| SCHEMBL107184 | 0.73 | ERCC1 (0.57) | ERCC1ERCC4HDAC1GAAHDAC6 | |
| SCHEMBL4023168 | 0.73 | ERCC1 (0.57) | ERCC1ERCC4HDAC1GAAHDAC6 | |
| SCHEMBL7279244 | 0.70 | ADRB2 (0.67) | ERCC1ERCC4MEN1KMT2AKDM4E | |
| SCHEMBL107957 | 0.69 | ARG1 (0.63) | ERCC1ERCC4MEN1KMT2AKDM4E | |
| Bromide SCHEMBL10436176 | 0.69 | ADRB2 (0.65) | ERCC1ERCC4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080334-B1 | 4-(N-(HYDROXYBENZYL)AMINOMETHYL)CYCLOHEXANE-1-CARBOXYLIC ACIDS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-10-17 | — | — | EP | claimed |