SCHEMBL11023701

SCHEMBL11023701

Sc1cccc(-c2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)c1S

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
IDO1 P14902 1/20 0.31
DNMT1 P26358 1/20 0.31
DNMT3L Q9UJW3 1/20 0.31
DNMT3A Q9Y6K1 1/20 0.31
NR1H2 P55055 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5890789 0.77 MEN1 (0.35) ALDH1A1TSHRIDO1
SCHEMBL31036021 0.77 MEN1 (0.35) ALDH1A1TSHRIDO1
SCHEMBL11304580 0.72 NR1H2 (0.35) ALDH1A1TSHRIDO1DNMT1DNMT3L
SCHEMBL11028228 0.70 TTR (0.30)
SCHEMBL29624838 0.69 TSHR (0.44) ALDH1A1TSHRIDO1
SCHEMBL2229304 0.69 TSHR (0.44) ALDH1A1TSHRIDO1
SCHEMBL3790605 0.68
SCHEMBL332474 0.68
SCHEMBL1968215 0.67
SCHEMBL11026582 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038459-B1 PROCESS FOR THE PREVENTION OF REVERSION DURING THE MANUFACTURE OF RUBBER VULCANISATES BAYER AG (DE) 1985-07-10 EP disclosed
US-4340695-A Vulcanization system, rubber mixture containing said system and a process of vulcanization BAYER AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
EP-0038459-A1 Process for the prevention of reversion during the manufacture of rubber vulcanisates BAYER AG (DE) 1981-10-28 EP disclosed