SCHEMBL29624838

SCHEMBL29624838

Clc1cccc(-c2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
NOTUM Q6P988 2/20 0.44
IDO1 P14902 1/20 0.44
CYP2D6 P10635 1/20 0.41
MAOA P21397 1/20 0.41
MAPK1 P28482 1/20 0.41
ADRA1A P35348 1/20 0.41
SCN4A P35499 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
PDE3A Q14432 1/20 0.41
SCN5A Q14524 1/20 0.41
SCN9A Q15858 1/20 0.41
SCN2A Q99250 1/20 0.41
SCN3A Q9NY46 1/20 0.41
SCN10A Q9Y5Y9 1/20 0.41
PNMT P11086 1/20 0.41
CYP2A6 P11509 2/20 0.39
CYP1A2 P05177 1/20 0.39
NUDT1 P36639 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2229304 1.00 TSHR (0.44) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL28988428 0.97 NOTUM (0.42) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL4456270 0.86 TSHR (0.46) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL4453481 0.85 NOTUM (0.41) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL440943 0.83 TSHR (0.52) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL30621941 0.82 NOTUM (0.42) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL4447012 0.82 NOTUM (0.42) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL4450215 0.81 CYP3A4 (0.42) TSHRNOTUMIDO1CYP2D6MAOA
SCHEMBL308792 0.81 CYP2A6 (0.52) TSHRNOTUMIDO1CYP2A6ALDH1A1
SCHEMBL4456481 0.80 ALDH1A1 (0.43) TSHRNOTUMIDO1CYP2D6MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-216805810-U Net-catching type unmanned aerial vehicle with counter-braking equipment 中航金城无人系统有限公司 2022-06-24 CN disclosed
CN-114634886-A Multifunctional microbial agent capable of degrading various halogenated organic pollutants simultaneously 河南科技大学 2022-06-17 CN disclosed
CN-114394680-A Application of microbial agent in degradation of various halogenated organic pollutants 河南科技大学 2022-04-26 CN disclosed