Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036021 | 1.00 | MEN1 (0.35) | MEN1KMT2ACDC25BMAPTMAPK1 | |
| SCHEMBL29109039 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL30648257 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL332474 | 0.82 | — | — | |
| Benzene SCHEMBL11814356 | 0.81 | ALDH1A1 (0.42) | KMT2AMAPTMAPK1HDAC8ALDH1A1 | |
| SCHEMBL439094 | 0.81 | ALDH1A1 (0.42) | KMT2AMAPTMAPK1HDAC8ALDH1A1 | |
| Benzene SCHEMBL27896534 | 0.81 | ALDH1A1 (0.42) | KMT2AMAPTMAPK1HDAC8ALDH1A1 | |
| Benzene SCHEMBL11823281 | 0.79 | MAPT (0.39) | MAPTPSMD14COPS5HDAC8 | |
| SCHEMBL11023701 | 0.77 | ALDH1A1 (0.32) | IDO1ALDH1A1TSHR | |
| Biphenyl SCHEMBL16581488 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AMAPTMAPK1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053173-B2 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1380572-A1 | POLYMERCAPTOPOLYPHENYLS AND METHOD FOR SYNTHESIS THEREOF | Japan Science and Technology Corporation (JP) | 2004-01-14 | — | — | EP | disclosed |
| JP-2003238525-A | TERPHENYLDI-, TRI- OR TETRA-THIOL OR THIOLATE AND METHOD FOR SYNTHESIZING THEM | JAPAN SCIENCE & TECHNOLOGY CORP | 2003-08-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | TMT1A, MSMO1, TST | MEN1 139/4885KMT2A 1680/4885CDC25B 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.