Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475931 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11024081 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL10858013 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11023139 | 0.84 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11020026 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11023389 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11020327 | 0.81 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11023509 | 0.81 | PDE3B (0.47) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11018951 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDGAAGALR3 | |
| SCHEMBL11025958 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDGAAGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |