Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CTSS | P25774 | 5/20 | 0.59 |
| ▸ | CTSK | P43235 | 4/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2547552 | 0.85 | CTSS (0.59) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL17442697 | 0.84 | NPC1 (0.50) | ATMALDH1A1LMNAALOX15HTT | |
| SCHEMBL11028734 | 0.84 | CTSS (0.62) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL12203694 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL9299789 | 0.83 | ATM (0.63) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL7939304 | 0.83 | ATM (0.63) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL3676166 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL3676162 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL29401299 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL6950136 | 0.83 | CTSS (0.64) | ATMCTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161801-A2 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |