SCHEMBL1102399

SCHEMBL1102399

CC(C)c1nccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
CYP2A6 P11509 2/20 0.57
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
PLAU P00749 2/20 0.52
F12 P00748 1/20 0.52
NCF1 P14598 1/20 0.52
NOS3 P29474 1/20 0.52
NOS1 P29475 1/20 0.52
NOS2 P35228 1/20 0.52
BACE1 P56817 1/20 0.52
MAPT P10636 3/20 0.51
HSD17B10 Q99714 2/20 0.51
NCOA3 Q9Y6Q9 1/20 0.46
CYP3A4 P08684 3/20 0.43
TSHR P16473 2/20 0.43
HRH4 Q9H3N8 1/20 0.43
CYP2C19 P33261 1/20 0.43
PLG P00747 1/20 0.43
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31732807 1.00 LMNA (0.59) LMNACYP2A6NPC1RAB9APLAU
Iodide SCHEMBL10722209 0.98 LMNA (0.58) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL27222070 0.86 LMNA (0.54) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL6748371 0.86 LMNA (0.54) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL27604309 0.86 LMNA (0.54) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL19099919 0.86 LMNA (0.54) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL6638130 0.86 LMNA (0.54) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL6246973 0.86 LMNA (0.54) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL4265753 0.86 LMNA (0.64) LMNACYP2A6NPC1RAB9APLAU
SCHEMBL3983719 0.86 LMNA (0.54) LMNACYP2A6NPC1RAB9APLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62221671-A None JP disclosed
WO-2025237291-A1 PREPARATION METHOD FOR ISOPROPYLISOQUINOLINE COMPOUND AND INTERMEDIATE THEREOF 上海翰森生物医药科技有限公司 2025-11-20 WO disclosed
CN-116283759-B Preparation method of 2-monofluoromethylquinoline and derivatives thereof 济南大学 2025-02-28 CN disclosed
US-20240299387-A1 HETEROCYCLIC EGFR INHIBITORS FOR USE IN THE TREATMENT OF CANCER BLUEPRINT MEDICINES CORPORATION 2024-09-12 US disclosed
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T REMIX THERAPEUTICS INC. 2024-07-18 US disclosed
US-20240208967-A1 Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof INVENTISBIO CO LTD (CN) 2024-06-27 US disclosed
EP-4328230-A2 AMINO ACID COMPOUNDS AND METHODS OF USE Pliant Therapeutics, Inc. (US) 2024-02-28 EP disclosed
US-20240025919-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF GENENTECH, INC. 2024-01-25 US disclosed
US-20240025919-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF GENENTECH, INC. 2024-01-25 US disclosed
US-20240025918-A1 KRAS G12D Inhibitors JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-01-25 US disclosed
WO-2006007700-A1 HEPATITIS C INHIBITOR DIPEPTIDE ANALOGS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-01-26 WO disclosed
WO-2006000085-A1 HEPATITIS C INHIBITOR PEPTIDE ANALOGS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-01-05 WO disclosed
EP-0152082-B1 AN ORGANIC SEMICONDUCTOR ELECTROLYTE CAPACITOR AND PROCESS FOR PRODUCING THE SAME NIPPON CHEMI-CON CORPORATION (JP) 1989-05-03 EP disclosed
US-4735823-A ELECTROLYTE IS MIXTURE OF ISOPROPYLQUINOLIDIUM TETRACYANOQUINODIMETHANE COMPLEX AND A LACTONE NIPPON CHEMI-CON CORPORATION (JP) 1988-04-05 US disclosed
JP-S62221671-A COMPLEX COMPOSITION FOR CAPACITOR NIPPON CHEMICON CORP 1987-09-29 JP disclosed
EP-0236842-A2 Fusible electrically conductive mixtures BAYER AG (DE) 1987-09-16 EP disclosed
US-4656560-A MIXTURE OF ISOPROPYLISOQUINOLINIUM TETRACYANOQUINODIMETHANE COMPLEX WITH A LACTONE NIPPON CHEMI-CON CORPORATION (JP) 1987-04-07 US disclosed
EP-0152082-A2 An organic semiconductor electrolyte capacitor and process for producing the same NIPPON CHEMI-CON CORPORATION (JP) 1985-08-21 EP disclosed
US-4337256-A ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) 1982-06-29 US disclosed
EP-0013411-A1 Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them TEIKOKU HORMONE MFG. CO., LTD. (JP) 1980-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299387-A1 HETEROCYCLIC EGFR INHIBITORS FOR USE IN THE TREATMENT OF CANCER EGFR, ERBB2, ERBB4 LMNA 4828/4885CYP2A6 2456/4885NPC1 2065/4885
US-20240208967-A1 Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof EGFR, WEE1, DPYD LMNA 3155/4885CYP2A6 213/4885NPC1 3163/4885
US-20240025919-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF AZI2, TET3, OXA1L LMNA 4245/4885CYP2A6 1444/4885NPC1 3948/4885
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T HNRNPAB, HNRNPC, HNRNPA1 LMNA 430/4885CYP2A6 4314/4885NPC1 459/4885
US-20240025918-A1 KRAS G12D Inhibitors KRAS, NRAS, HRAS LMNA 2462/4885CYP2A6 3433/4885NPC1 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.