Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028996 | 0.83 | TSHR (0.44) | OPRM1OPRD1OPRK1HDAC8MEN1 | |
| SCHEMBL31669038 | 0.82 | KDM4E (0.57) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7744084 | 0.82 | KDM4E (0.57) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3319088 | 0.82 | KDM4E (0.57) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7743516 | 0.82 | KDM4E (0.57) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16140165 | 0.81 | TNF (0.41) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL8121954 | 0.81 | KDM4E (0.60) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL8702078 | 0.81 | KDM4E (0.60) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL30377815 | 0.81 | KDM4E (0.60) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11030539 | 0.80 | PNMT (0.62) | ADRA2APNMTADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088350-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0088350-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1983-09-14 | — | — | EP | disclosed |