Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478957 | 0.85 | NQO2 (0.41) | KMT2ATSHRNPSR1CA1CA2 | |
| SCHEMBL10515637 | 0.83 | HTR2A (0.49) | KMT2A | |
| SCHEMBL11028997 | 0.83 | TSHR (0.45) | TSHRNPSR1SLC6A2SLC6A4 | |
| SCHEMBL23119015 | 0.82 | TSHR (0.60) | SMN1; SMN2TSHRNPSR1SLC18A2MAPT | |
| SCHEMBL4853532 | 0.82 | TSHR (0.60) | SMN1; SMN2TSHRNPSR1SLC18A2MAPT | |
| Hydrochloric Acid SCHEMBL19953531 | 0.81 | TSHR (0.62) | GAASMN1; SMN2TSHRNPSR1SLC18A2 | |
| Hydrochloric Acid SCHEMBL2790413 | 0.81 | TSHR (0.62) | GAASMN1; SMN2TSHRNPSR1SLC18A2 | |
| SCHEMBL11030540 | 0.80 | ALDH1A1 (0.49) | KMT2AGAASMN1; SMN2TBXA2RALDH1A1 | |
| SCHEMBL12193294 | 0.80 | KMT2A (0.48) | KMT2AMEN1TSHRMAOASLC18A2 | |
| SCHEMBL8259309 | 0.79 | CA1 (0.43) | KMT2ATSHRNPSR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088350-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0088350-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1983-09-14 | — | — | EP | disclosed |